Search on: CHLORIDE, PROTAMINE 
Descriptors Found: 1
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Descriptor English:   Protamines 
Descriptor Spanish:   Protaminas 
Descriptor Portuguese:   Protaminas 
Synonyms English:   Protamine Chloride
Chloride, Protamine
Sulfate, Protamine
Protamine Sulfate  
Tree Number:   D12.776.660.750
D12.776.664.750
Definition English:   A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692) 
Indexing Annotation English:   heparin antag
Pharmacological Action:   Heparin Antagonists
 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   23432 
Unique Identifier:   D011479 

Occurrence in VHL:
 

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